| 货号 | 0236/100 |
| 别名 | (±)-3-Piperidine carboxylic acid |
| 供应商 | Tocris |
| 生物活性 | GABA uptake inhibitor. IC50 values are 8, 38, 106 and 2370 μM for hGAT-1, rGAT-2, hGAT-3 and hBGT-1 respectively. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 计算分子量 | 129.16 |
| 分子式 | C6H11NO2 |
| 可溶性/溶解性 | Soluble to 100 mM in water |
| CAS号 | 60252-41-7 |
| 参考文献 | Bordenet al (1994) Tiagabine, SK&F 89976-A, CI 966, and NNC-711 are selective for the cloned GABA transporter GAT-1. Eur.J.Pharmacol. 269 219. PMID: 7851497. Krogsgaard-Larsenet al (1981) GABA agonists, antagonists and uptake inhibitors. Design and therapeutic aspects. J.Med.Chem. 24 1377. PMID: 6118436. Schousboeet al (1979) Effects of GABA analogues of restricted conformation on GABA transport in astrocytes and brain cortex slices and on GABA binding. J.Neurochem. 33 181. PMID: 458448. |