| 货号 | 2968/50 |
| 别名 | (7α,17α)-7-(Acetylthio)-17-hydroxy-3- |
| 供应商 | Tocris |
| 生物活性 | Competitive mineralocorticoid (aldosterone) receptor antagonist that exhibits antihypertensive activity in vivo. Also displays antiandrogen activity and inhibits steroid hormone biosynthesis. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >98 % |
| 计算分子量 | 416.57 |
| 分子式 | C24H32O4S |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 50 mM in ethanol |
| CAS号 | 52-01-7 |
| 参考文献 | Yeet al (2009) Contrasting effects of eplerenone and spironolactone on adrenal cell steroidogenesis. Horm.Metab.Res. 41 35. PMID: 18819053. Strutherset al (2008) A comparison of the aldosterone-blocking agents eplernone and spironolactone. Clin.Cardiol. 31 153. PMID: 18404673. Delyaniet al (2000) Mineralocorticoid receptor antagonists: the evolution of utility and pharmacology. Kidney Int. 57 1408. PMID: 10760075. |