货号 | 0959/100 |
别名 | N-(3-Aminopropyl)-1,4-butanediamine |
供应商 | Tocris |
生物活性 | Binds to the polyamine modulatory site of the NMDA receptor and has been described as an agonist based on its ability to enhance the binding of [3H]-MK801. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
计算分子量 | 254.63 |
分子式 | C7H19N3.3HCl |
可溶性/溶解性 | Soluble to 100 mM in water |
CAS号 | 334-50-9 |
参考文献 | Kishiet al (1998) Spermidine, a polyamine site agonist, attenuates working memory deficits caused by blockade of hippocampal muscarinic receptors and mGluRs in rats. Brain Res. 793 311. PMID: 9630697. Muniret al (1993) Polyamines modulate the neurotoxic effects of NMDA in vivo. Brain Res. 616 163. PMID: 8358608. Williamset al (1989) Effects of polyamines on the binding of [3H]-MK801 to the N-methyl-D-aspartate receptor: pharmacological evidence for the existence of a polyamine recognition site. Mol.Pharmacol. 36 375. PMID: 2554112. |