| 货号 | 0727/50 |
| 别名 | PDTC |
| 供应商 | Tocris |
| 生物活性 | This inhibitor of nuclear factor κB (NF-κB) prevents the increase in NO-synthase mRNA by interleukin-1, without affecting the formation of NO-synthase mRNA produced by cAMP. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 计算分子量 | 164.28 |
| 分子式 | C5H12N2S2 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| CAS号 | 5108-96-3 |
| 参考文献 | Besshoet al (1994) Pyrrolidine dithiocarbamate, a potent inhibitor of nuclear factor κB (NF-κB) activation, prevents apoptosis in human promyelocytic leukemia HL-60 cells and thymocytes. Biochem.Pharmacol. 48 1883. PMID: 7986199. Eberhardtet al (1994) Pyrrolidine dithiocarbamate differentially affects 1β- and cAMP-induced NO-synthase expression in rat renal mesangial cells. Biochem.Biophys.Res.Commun. 200 163. PMID: 7513157. Schini-Kerth (1994) Pyrrolidine dithiocarbamate selectively prevents the expression of the inducible nitric oxide synthase in the rat aorta. Eur.J.Pharmacol. 265 83. PMID: 7533726. |