货号 | 3287/100 |
别名 | 2-Chloro-10-[3[(4-methyl-1-piperazi |
供应商 | Tocris |
生物活性 | D2 receptor antagonist. Also interacts with 5-HT3 and nAChR. Displays antipsychotic, antispasmodic, antiemetic and antinociceptive activity in vivo. |
运输条件 | Blue Ice |
存放说明 | Ambient |
纯度 | >99 % |
计算分子量 | 606.09 |
分子式 | C20H24ClN3S ?2C4H4O4 |
可溶性/溶解性 | Soluble to 25 mM in DMSO |
CAS号 | 84-02-6 |
参考文献 | Satohet al (2005) The antipsychotic and antiemetic drug prochlorperazine delays the ventricular repolarization of the in situ canine heart. J.Pharm.Sci. 97101. Ghelardiniet al (2004) Prochlorperazine induces central antinociception mediated by the muscarinic system. Pharmacol.Res. 50 351. PMID: 15225680. Lummis and Baker (1997) Radioligand binding and photoaffinity labeling studies show a direct interaction of phenothiazenes at 5-HT3 receptors. Neuropharmacology 36 665. PMID: 9225292. |