| 货号 | 4744/1 |
| 供应商 | Tocris |
| 生物活性 | Potent antagonist of the integrin αvβ3-vitronectin interaction (IC50 = 25.72 nM). Blocks proliferation and induces apoptosis in HUVECs; antiangiogenic. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 720.78 |
| 分子式 | C30H48N12O9< |
| 可溶性/溶解性 | Soluble to 1 mg/ml in 20% acetonitrile - 0.1% acetic acid |
| 序列号 | HSDVHK (Modifications: Lys-6 = C-terminal amide) |
| 参考文献 | Banget al (2011) Pharmacoproteomic analysis of a novel cell-permeable inhibitor of tumor-induced angiogenesis. Mol.Cell Proteomics 10 M110. PMID: 21558493. Choiet al (2010) Site-specific inhibition of integrin alpha v beta 3-vitronectin association by a ser-asp-val sequence through an Arg-Gly-Asp-binding site of the integrin. Proteomics 10 72. PMID: 19882657. Leeet al (2004) High-throughput screening of novel peptide inhibitors of an integrin receptor from the hexapeptide library by using a protein microarray chip. J.Biomol.Screen. 9 687. PMID: 15634795. |