| 货号 | 0238/100 |
| 别名 | L-Serine-O-phosphate;L-SOP |
| 供应商 | Tocris |
| 生物活性 | Group III metabotropic glutamate receptor agonist; analog of L-AP4 (Cat. No. 0103). Neuroprotective against excitotoxicity in cortical cell cultures. Inhibits proliferation and enhances neuronal differentiation in progenitor cells. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 计算分子量 | 185.07 |
| 分子式 | C3H8NO6P |
| 可溶性/溶解性 | Soluble to 100 mM in water |
| CAS号 | 407-41-0 |
| 参考文献 | Yanget al (2016) A chemical biology route to site-specific authentic protein modifications. Science 354 623. PMID: 27708052. Parket al (2011) Expanding the genetic code of Escherichia coli with phosphoserine. Science 333 1151. PMID: 21868676. Saxeet al (2007) A phenotypic small-molecule screen identifies an orphan ligand-receptor pair that regulates neural stem cell differentiation. Chem.Biol. 14 1019. PMID: 17884634. Brunoet al (1996) Activation of group III metabotropic glutamate receptors is neuroprotective in cortical cultures. Eur.J.Pharmacol. 310 61. PMID: 8880068. Eriksen and Thomsen (1995) [3H]-L-2-amino-4-phosphonobutyrate labels a metabotropic glutamate receptor, mGluR4a. Br.J.Pharmacol. 116 3279. PMID: 8719808. Thoreson and Ulphani (1995) Pharmacology of selective and non-selective metabotropic glutamate receptor agonists at L-AP4 receptors in ON bipolar cells. Brain Res. 676 93. PMID: 7796182. |