| 货号 | 0997/50 |
| 别名 | 1,2,3,4,10,14b-Hexahydro-2-methyldi |
| 供应商 | Tocris |
| 生物活性 | Non-selective 5-HT2 receptor antagonist (Ki values are 0.0080 and 0.0081 μM for human 5-HT2A and 5-HT2C receptors expressed in HEK293 cells respectively). Has moderate affinity for 5-HT6. Antidepressant. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 300.83 |
| 分子式 | C18H20N2.HCl |
| 可溶性/溶解性 | Soluble to 10 mM in water |
| CAS号 | 21535-47-7 |
| 参考文献 | Jensenet al (2013) Design, synthesis, and pharmacological characterization of N- and O-substituted 5,6,7,8-tetrahydro-4H-isoxazolo[4,5-dazepin-3-ol analogues: novel 5-HT2A/5-HT2C receptor agonists with pro-cognitive properties. J.Med.Chem. 56 1211. PMID: 23301527. Hoyeret al (1994) VII. International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (serotonin). Pharmacol.Rev. 46 157. PMID: 7938165. Leonard (1982) On the mode of action of mianserin. Adv.Biochem.Psychopharmacol. 31 301. PMID: 6282060. Merck Index 126260. |