货号 | 3213/50 |
别名 | 3,7-bis(Dimethylamino)phenazathioni |
供应商 | Tocris |
生物活性 | Biological stain and redox indicator. Inhibits tau filament formation (IC50 = 1.9 μM). Also inhibits soluble guanylyl cyclase. |
运输条件 | Blue Ice |
存放说明 | Ambient |
计算分子量 | 319.85 |
分子式 | C16H18ClN3S |
可溶性/溶解性 | Soluble to 10 mM in water and to 10 mM in DMSO |
CAS号 | 61-73-4 |
参考文献 | Taniguchiet al (2005) Inhibition of heparin-induced tau filament formation by phenothiazines, polyphenols, and porphyrins. J.Biol.Chem. 280 7614. PMID: 15611092. Hwanget al (1998) Comparison of two soluble guanylyl cyclase inhibitors, methylene boue and ODQ, on sodium nitroprusside-induced relaxation in guinea-pig trachea. Br.J.Pharmacol. 125 1158. PMID: 9863642. Wischiket al (1996) Selective inhibition of Alzheimer disease-like tau aggregation by phenothiazines. Neurobiology 9311213. |