货号 | 2873/1 |
别名 | Leuoprorelin |
供应商 | Tocris |
生物活性 | Gonadotropin-releasing hormone (GnRH, luteinizing hormone-releasing hormone, LHRH) receptor agonist. Suppresses estradiol, LH and FSH serum levels and represses the growth of experimental rat endometriosis. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
计算分子量 | 1209.41 |
分子式 | C59H84N16O12 |
可溶性/溶解性 | Soluble to 0.50 mg/ml in water |
CAS号 | 74381-53-6 |
序列号 | XHWSYLLRP (Modifications: X1 = Glp, Pro-9 = Pro-NHEt) |
参考文献 | Udayet al (2007) LHRH antagonist attenuates the effect of fluoxetine on marble-burying behavior in mice. Eur.J.Pharmacol. 563 155. PMID: 17368614. Salvadoret al (2001) Effects of the luteinising hormone-releasing hormone (LH-RH) agonist leuprolide on adenylyl cyclase regulation through G-protein coupled receptors in rat ventral prostate. Eur.J.Pharmacol. 37641. Okadaet al (1988) One-month release injectable microcapsules of a luteinizing hormone-releasing hormone agonist (leuprolide acetate) for treating experimental endometriosis in rats. J.Pharmacol.Exp.Ther. 244 744. PMID: 3126294. |