| 货号 | 0223/1G |
| 别名 | 4-Hydroxyquinoline-2-carboxylic acid |
| 供应商 | Tocris |
| 生物活性 | Broad spectrum EAA antagonist. Putative GPR35 ligand. Kynurenic acid sodium salt also available (Cat. No. 3694). |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >98 % |
| 计算分子量 | 189.17 |
| 分子式 | C10H7NO3 |
| 可溶性/溶解性 | Soluble to 50 mM in DMSO and to 100 mM in 1eq. NaOH |
| 参考文献 | Wanget al (2006) Kynurenic acid as a ligand for orphan G protein-coupled receptor GPR35. J.Biol.Chem. 281 22021. PMID: 16754668. Pittalugaet al (1997) The 'kynurenate test,' a biochemical assay for putative cognition enhancers. J.Pharmacol.Exp.Ther. 283 82. PMID: 9336311. Stone and Burton (1988) NMDA receptors and ligands in the vertebrate CNS. Prog.Neurobiol. 30 333. PMID: 2830636. Perkins and Stone (1982) An iontophoretic investigation of the actions of convulsant kynurenines and their interaction with the endogenous excitant quinolinic acid. Brain Res. 247 184. PMID: 6215086. |