| 货号 | 3435/10 |
| 供应商 | Tocris |
| 生物活性 | Endogenous insulin receptor agonist (Ki = 4.85 nM). Decreases plasma glucose levels, proteolysis, lipolysis and gluconeogenesis and increases glycogen and fatty acid synthesis in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 5807.57 |
| 分子式 | C257H383N65O77S6 |
| 可溶性/溶解性 | Soluble to 20 mg/ml in 0.01 M hydrochloric acid |
| CAS号 | 11061-68-0 |
| 序列号 | GIVEQCCTSICSLYQLENYCN FVNQHLCGSHLVEALYLVCGERGFFYTPKT (Modifications: Disulfide bridge between 6 - 11, 7 -7*, 20 - 19*) |
| 参考文献 | Leney and Tavare (2009) The molecular basis of insulin-stimulated glucose uptake: signalling, trafficking and potential drug targets. J.Endocrinol. 203 1. PMID: 19389739. Ouet al (2001) The binding characteristics of insulin-MTX to insulin receptor. Hua.Xi.Yi.Ke.Da.Xue.Xue.Bao. 32 538. PMID: 12528542. Torlinskaet al (2000) Age dependent changes of insulin receptors in rat tissues. J.Physiol.Pharmacol. 51 871. PMID: 11220495. |