| 货号 | 2845/50 |
| 别名 | 3,7-Dihydro-1-methyl-3-(2-methylpro |
| 供应商 | Tocris |
| 生物活性 | Phosphodiesterase inhibitor (IC50 values are 13, 18, 19, 32 and 50 μM for PDE4, PDE3, PDE1, PDE5 and PDE2 respectively). Suppresses α-adrenoceptor-mediated 5-HT release from neuroendocrine epithelial cells (IC50 = 1.3 μM). Facilitates differentiation of neural progenitor cells in vitro. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 222.24 |
| 分子式 | C10H14N4O2 |
| 可溶性/溶解性 | Soluble to 75 mM in DMSO and to 50 mM in ethanol |
| CAS号 | 28822-58-4 |
| 参考文献 | Lepskiet al (2013) cAMP promotes the differentiation of neural progenitor cells in vitro via modulation of voltage-gated calcium channels. Front.Cell Neurosci. 7 155. PMID: 24065885. Freitaget al (1998) Phosphodiesterase inhibitors suppress α2-adrenoceptor-mediated 5-hydroxytryptamine release from tracheae of newborn rabbits. Eur.J.Pharmacol. 354 67. PMID: 9726632. |