| 货号 | 0691/500 |
| 别名 | 2,6-bis(Diethanolamino)-4,8-dipiper |
| 供应商 | Tocris |
| 生物活性 | Coronary vasodilator; adenosine transport inhibitor. Phosphodiesterase inhibitor (IC50 values are 0.37, 0.38, 0.45, 0.9 and 4.5 μM |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 504.63 |
| 分子式 | C24H40N8O4 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 10 mM in ethanol |
| CAS号 | 58-32-2 |
| 参考文献 | Lin and Buolamwiniet al (2007) Synthesis, flow cytometric evaluation, and identification of highly potent dipyridamole analogues as equilibrative nucleoside transporter 1 inhibitors. J.Med.Chem. 50 3906. PMID: 17636949. Fujishigeet al (1999) Cloning and characterization of a novel human phosphodiesterase that hydrolyzes both cAMP and cGMP (PDE10A). J.Biol.Chem. 274 18438. PMID: 10373451. Meesteret al (1998) Pharmacological analysis of the activity of the adenosine uptake inhibitor, dipyridamole, on the sinoatrial and atrioventricular nodes of the guinea-pig. Br.J.Pharmacol. 124 729. PMID: 9690865. Soderlinget al (1998) Cloning and characterization of a cAMP-specific cyclic nucleotide phosphodiesterase. Proc.Natl.Acad.Sci.U.S.A. 95 8991. PMID: 9671792. |