| 货号 | 1126/100 |
| 别名 | (11β,16α)-9-Fluoro-11,17,21-trihydrox |
| 供应商 | Tocris |
| 生物活性 | Glucocorticoid; anti-inflammatory. Reduces levels of activated NF-κB in immature dendritic cells (DCs) and inhibits differentiation into mature DCs. Induces differentiation of human mesenchymal stem cells (MSCs). Also induces autophagy in acute lymphoblastic leukemia (ALL) cell lines. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >98 % |
| 计算分子量 | 392.47 |
| 分子式 | C22H29FO5 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| CAS号 | 50-02-2 |
| 参考文献 | Sittichokechaiwutet al (2010) Short bouts of mechanical loading are as effective as dexamethasone at inducing matrix production by human bone marrow mesenchymal stem cell. Eur.Cell Mater. 20 45. PMID: 20648425. Laaneet al (2009) Cell death induced by dexamethasone in lymphoid leukemia is mediated through initiation of autophagy. Cell Death Differ. 16 1018. PMID: 19390558. Matasicet al (1999) Dexamethasone inhibits dendritic cell maturation by redirecting differentiation of a subset of cells. J.Leukoc.Biol. 66 909. PMID: 10614771. Teixeiraet al (1996) Effects of dexamethasone and cyclosporin A on the accumulation of eosinophils in acute cutaneous inflammation in the guinea-pig. Br.J.Pharmacol. 118 317. PMID: 8735633. Merck Index 122986. |