货号 | 0457/500 |
别名 | 3-Chloro-10,11-dihydro-N,N-dimethyl |
供应商 | Tocris |
生物活性 | Potent, selective 5-HT uptake blocker. Antidepressant. Binds to the human 5-HT transporter with a Ki of 0.05 nmol/l. |
运输条件 | Blue Ice |
存放说明 | Ambient |
纯度 | >98 % |
计算分子量 | 351.32 |
分子式 | C19H23ClN2.HCl |
可溶性/溶解性 | Soluble to 100 mM in water |
CAS号 | 17321-77-6 |
参考文献 | Owenset al (1997) Neurotransmitter receptor and transporter binding profile of antidepressants and their metabolites. J.Pharmacol.Exp.Ther. 283 1305. PMID: 9400006. Ortiz and Artiga (1992) Effects of monoamine uptake inhibitors on extracellular and platelet 5-hydroxytryptamine in rat blood: different effects of clomipramine and fluoxetine. Br.J.Pharmacol. 105 941. PMID: 1387022. McTavish and Benfield (1990) Clomipramine. An overview of its pharmacological properties and a review of its therapeutic use in obsessive compulsive disorder and panic disorder. Drugs 39 136. PMID: 2178909. Merck Index 122447. |