货号 | 0846/1G |
别名 | 6,6'-[(3,3-Dimethoxy[1,1'-biphenyl]-4 |
供应商 | Tocris |
生物活性 | Potent inhibitor of L-glutamate uptake into synaptic vesicles. Allosterically inhibits macrophage migration inhibitory factor (MIF) (IC50 = 0.81 μM); inhibits MIF proinflammatory activity. |
运输条件 | Blue Ice |
存放说明 | Ambient |
计算分子量 | 992.79 |
分子式 | C34H24N6Na4< |
可溶性/溶解性 | Soluble to 100 mM in water |
参考文献 | Baiet al (2012) A novel allosteric inhibitor of macrophage migration inhibitory factor (MIF). J.Biol.Chem. 287 30653. PMID: 22782901. Rosethet al (1995) Uptake of L-glutamate into rat brain synaptic vesicles: effect of inhibitors that bind specifically to the glutamate transport. J.Neurochem. 65 96. PMID: 7790899. Fonnumet al (1994) Inhibitors of amino acid uptake into vesicles. J.Neurochem. 63 Suppl. 1 S49A. |