货号 | 3096/50 |
别名 | (3β,20β)-3-(3-Carboxy-1-oxopropoxy)-1 |
供应商 | Tocris |
生物活性 | Glucocorticoid that inhibits 11β-hydroxysteroid dehydrogenase (11-HSD) and blocks gap junction communication. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
纯度 | >98 % |
计算分子量 | 614.72 |
分子式 | C34H48Na2O7 |
可溶性/溶解性 | Soluble to 100 mM in water |
CAS号 | 7421-40-1 |
参考文献 | Sagar and Larson (2006) Carbenoxolone inhibits junctional trasnfer and upregulates connexin43 expression by a protein kinase A-dependent pathway. J.Cell.Biochem. 98 1543. PMID: 16552723. Jellincket al (1993) Differential inhibition of 11 beta-hydroxysteroid dehydrogenase by carbenoxolone in rat brain regions and peripheral tissues. J.Steroid Biochem.Mol.Biol. 46 209. PMID: 8664169. |