货号 | 3108/50 |
别名 | 3-(Aminosulfonyl)-5-(butylamino)-4- |
供应商 | Tocris |
生物活性 | Loop diuretic that inhibits the Na+/2Cl-/K+ (NKCC) cotransporter. More potent than furosemide (Cat. No. 3109). |
运输条件 | Blue Ice |
存放说明 | Ambient |
纯度 | >99 % |
计算分子量 | 364.42 |
分子式 | C17H20N2O5S |
可溶性/溶解性 | Soluble to 100 mM in DMSO and to 75 mM in ethanol |
CAS号 | 28395-03-1 |
参考文献 | Moritaet al (1999) Functional evidence for involvement of bumetanide-sensitive Na+K+2Cl- cotransport in the hepatoportal Na+ receptor of the sprague-dawley rat. Neurosci.Letts. 26465. Isenring and Forbush (1997) Ion and bumetanide binding by the Na-K-Cl cotransporter. J.Biol.Chem. 272 24556. PMID: 9305921. O'Gradyet al (1987) Characteristics and functions of Na-K-Cl cotransport in epithelial tissues. Am.J.Physiol. 253 C177. PMID: 3303961. |