Posaconazole
货号：
14737-1mg 基本售价：
1050.0 元 规格：
1 mg
产品信息
概述| 货号 | 14737-1mg |
| 描述 | Posaconazole is a broad-spectrum triazole active against various yeasts and molds, including Aspergillus,Candida,Fusarium, and Zygomycetes.1 Posaconazole inhibits the growth of fungi by inhibiting the lanosterol 14α-demethylase enzyme (IC50s range from 7-200 nM), which results in a disruption the synthesis of ergosterol, a key sterol necessary for fungal cell membrane integrity and for the function of certain membrane-bound proteins.2 |
| 别名 | Noxafil;POS;SCH 56592; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Herbrecht, R.,Nivoix, Y.,Fohrer, C., et al. Management of systemic fungal infections: Alternatives to itraconazole. J. Antimicrob. Chemother. 56(Suppl 1), i39-i48 (2005).
2.Munayyer, H.K.,Mann, P.A.,Chau, A.S., et al. Posaconazole is a potent inhibitor of sterol 14α-demethylation in yeasts and molds. Antimicrobial Agents and Chemotherapy 48(10), 3690-3696 (2004).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 700.8 |
| 分子式 | C37H42F2N8O4 |
| CAS号 | 171228-49-2 |
| 稳定性 | ≥ 2 years |
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