货号 | 1470/10 |
别名 | N-(2-Piperidylmethyl)-2,5-bis-(2,2, |
供应商 | Tocris |
生物活性 | Open Na+ channel blocker that inhibits fast Na+ current in cardiac muscle in a use- and concentration-dependent manner. Orally-active class Ic antiarrhythmic agent. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
纯度 | >99 % |
计算分子量 | 474.4 |
分子式 | C17H20F6N2O3.C2H4O2 |
可溶性/溶解性 | Soluble to 25 mM in water and to 100 mM in DMSO |
CAS号 | 54143-56-5 |
参考文献 | Rouet and Ducouret (1994) Use-and concentration-dependent effects of flecainide in guinea pig right ventricular muscle. J.Cardiovasc.Pharmacol. 24 177. PMID: 7526048. Singhet al (1984) The electrophysiology and pharmacology of verapamil, flecainide, and amiodarone: correlations with clinical effects and antiarrhythmic actions. Ann.N.Y.Acad.Sci. 17 251. PMID: 6395762. Banittet al (1977) Antiarrhythmics. 2. Synthesis and antiarrhythmic activity of N-(piperidylalkyl)trifluoroethoxybenzamides. J.Med.Chem. 20 821. PMID: 874956. |