| 货号 | 0845/1G |
| 别名 | 6,6-[(3,3'-Dimethyl[1,1'-biphenyl]-4, |
| 供应商 | Tocris |
| 生物活性 | Potent inhibitor of L-glutamate uptake into synaptic vesicles. Also inhibits AMPA and kainate receptor-mediated currents (IC50 values are 220 and 150 nM respectively). P2X-selective purinoceptor antagonist. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >95 % |
| 计算分子量 | 960.82 |
| 分子式 | C34H24N6Na4< |
| 可溶性/溶解性 | Soluble to 10 mM in water |
| 参考文献 | Schurmannet al (1997) Differential modulation of AMPA receptor mediated currents by Evans Blue in postnatal rat hippocampal neurones. Br.J.Pharmacol. 121 237. PMID: 9154333. Price and Raymond (1996) Evans blue antagonizes both α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate and kainate receptors and modulates desensitization. Mol. Pharmacol. 50 1665. PMID: 8967991. Wittenburget al (1996) P2-purinoceptor antagonists:II blockade of P2-purinoceptor subtypes and ecto-nucleotidase by compounds related to Evans blue and trypan blue. Naunyn Schmiedebergs Arch.Pharmacol. 354 491. PMID: 8897453. Rosethet al (1995) Uptake of L-glutamate into rat brain synaptic vesicles: effect of inhibitors that bind specifically to the glutamate transporter. J.Neurochem. 65 96. PMID: 7790899. Merck Index 123952. |