| 货号 | 1089/10 |
| 别名 | 8-Bromoguanosine cyclic 3',5'-monophosphate sodium salt |
| 供应商 | Tocris |
| 生物活性 | Membrane permeable cGMP analog that activates protein kinase G (PKG). 4.3-fold more potent than cGMP in activating PKG1α and promotes relaxation of tracheal and vascular smooth muscle tissue in vitro. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 446.09 |
| 分子式 | C10H10BrN5NaO7P |
| 可溶性/溶解性 | Soluble to 100 mM in water |
| CAS号 | 51116-01-9 |
| 参考文献 | Sekharet al (1992) Relaxation of pig coronary arteries by new and potent cGMP analogs that selectively activate type 1α, compared with type 1β, cGMP-dependent protein kinase. Mol.Pharmacol. 42 103. PMID: 1321950. Buchanet al (1991) Modulation of agonist-induced calcium mobilisation in bovine aortic endothelial cells by phorbol myristate acetate and cyclic AMP but not cyclic GMP. Br.J.Pharmacol. 104 361. PMID: 1665733. Ignarroet al (1974) Stimulation of phagocytic release of neutral protease from human neutrophils by cholinergic amines and cyclic 3',5'-guanosine monophosphate. J.Immunol. 112 210. PMID: 4359834. |