UF 010 (10 MG)
货号：
5588/10 基本售价：
971.6 元 规格：
10 mg
产品信息
概述| 货号 | 5588/10 |
| 别名 | 4-Bromo-N'-butylbenzohydrazide |
性能| 供应商 | Tocris |
| 生物活性 | Class I HDAC inhibitor (IC50 values are 0.06, 0.1, 0.5 and 1.5 μM for HDACs 3, 2, 1 and 8, respectively). Exhibits >6-fold selectivity over other HDACs. Induces accumulation of acetylated histones in HCT116 cells in vitro. Inhibits proliferation of a range of cancer cell lines. Arrests cells at G1/S transition. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 271.15 |
| 分子式 | C11H15BrN2O |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| 参考文献 | Wanget al (2015) Identification of histone deacetylase inhibitors with benzoylhydrazide scaffold that selectively inhibit class I histone deacetylases. Chem.Biol. 22 273. PMID: 25699604. |
