TC-E 5003 (50 MG)
货号：
5099/50 基本售价：
971.6 元 规格：
50 mg
产品信息
概述| 货号 | 5099/50 |
| 别名 | N,N'-(Sulfonyldi-4,1-phenylene)bis(2-chloroacetamide) |
性能| 供应商 | Tocris |
| 生物活性 | Selective protein arginine methyltransferase 1 (PRMT1) inhibitor (IC50 = 1.5 μM); exhibits no inhibitory activity against CARM1 and Set7/9 methyltransferases. Inhibits growth of MCF7a breast cancer cells and LNCaP prostate cancer cells. Attenuates androgen-induced gene expression in LNCaP cells. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 401.26 |
| 分子式 | C16H14Cl2N2< |
| 可溶性/溶解性 | Soluble to 50 mM in DMSO |
| 参考文献 | Bissingeret al (2011) Acyl derivatives of p-aminosulfonamides and dapsone as new inhibitors of the arginine methyltransferase hPRMT1. Bioorg.Med.Chem. 19 3717. PMID: 21440447. |
