| 货号 | 2024/1 |
| 供应商 | Tocris |
| 生物活性 | Selectiveμ opioid receptor agonist (IC50 values are 5.5 and > 10000 nM for inhibition of 125I-FK 33,824 and 125I-DADLE binding to μandδ sites respectively). Produces naloxone-reversible analgesia, catalepsy and hyperthermia following central administration in rats in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 535.64 |
| 分子式 | C29H37N5O5 |
| 可溶性/溶解性 | Soluble to 1 mg/ml in water |
| 序列号 | YPFP (Modifications:Phe-3 = N-methyl-Phe, Pro-4 = C-terminal amide) |
| 参考文献 | Xinet al (1997) Body temperature and analgesic effects of selective mu and kappa opioid receptor agonists microdialyzed into rat brain. J.Pharmacol.Exp.Ther. 281 499. PMID: 9103537. Meyer and Meyer (1993) Behavioral effects of the μ-opioid peptide agonists DAMGO, DALDA and PL017 on locomotor activities. Pharmacol.Biochem.Behav. 46 391. PMID: 8265694. Changet al (1983) Potent morphiceptin analogs: structure activity relationships and morphine-like activities. J.Pharmacol.Exp.Ther. 227 403. PMID: 6313901. |