| 货号 | 4153/1 |
| 别名 | (1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-1a, |
| 供应商 | Tocris |
| 生物活性 | Protein kinase C activator. Induces contraction of vascular smooth muscle and inhibits MLC phosphatase (MLCP) in vascular smooth muscle. Activity does not alter intracellular Ca2+ concentration. Also inhibits the activity of Na+,K+ ATPase in OK cells. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 504.61 |
| 分子式 | C28H40O8 |
| 可溶性/溶解性 | Soluble to 50 mM in DMSO |
| 参考文献 | Sakaiet al (2010) Augmented PDBu-mediated contaction of bronchial smooth muscle of mice with antigen-induced airway hyperresponsiveness. J.Smooth Muscle Res. 46 259. PMID: 21187674. Horiet al (1999) Presynaptic mechanism for phorphol ester-induced synaptic potentiation. J.Neurosci. 19 7262. PMID: 10460232. Middletonet al (1993) Heterogeneity of protein kinase C-mediated rapid regulation of Na/K-ATPase in kidney epithelial cells. J.Biol.Chem. 268 15958. PMID: 8393456. |