| 货号 | 2242/100 |
| 别名 | α-(Aminomethyl)-4-hydroxybenzenemeth |
| 供应商 | Tocris |
| 生物活性 | Invertebrate biogenic amine neurotransmitter, related to noradrenalin, that is an adrenoceptor agonist. Stimulates lipolysis in mammalian adipocytes via activation of β3 receptors. Has dual effect on glucose transport in adipocytes: inhibits transport via β3 receptor activation but stimulates transport when oxidized by MAO. Also activates human α2A receptors, inhibiting subsequent cAMP production. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 189.64 |
| 分子式 | C8H11NO2.HCl |
| 可溶性/溶解性 | Soluble to 100 mM in water |
| CAS号 | 770-05-8 |
| 参考文献 | Visentinet al (2001) Dual action of octopamine on glucose transport into adipocytes: inhibition via β3-adrenoceptor activation and stimulation via oxidation by amine oxidases. J.Pharmacol.Exp.Ther. 299 96. PMID: 11561068. Carpeneet al (1999) Selective activation of β3-adrenoceptors by octopamine: comparative studies in mammalian fat cells. Naunyn-Schmied.Arch.Pharmacol. 359310. Roeder (1999) Octopamine in invertebrates. Prog.Neurobiol. 59 533. PMID: 10515667. Airriesset al (1997) Selective inhibition of adenylyl cyclase by octopamine via a human cloned α2A-adrenoceptor. Br.J.Pharmacol. 122 191. PMID: 9313925. |