| 货号 | 2841/50 |
| 别名 | (1E,6E)-1,7-Bis(4-hydroxy-3-methoxy |
| 供应商 | Tocris |
| 生物活性 | Antitumor, anti-inflammatory and antioxidant agent. Downregulates expression of reactive-oxygen-generating enzymes (cyclooxygenase, lipoxygenase, iNOS), TNFα, IL-1, IL-6, PKC, EGFR, NF-κB, IκB kinase and more. Upregulates expression of PPARγ, p53, Nrf2. Also displays antimicrobial, antidiabetic neuro- and cardioprotective properties in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 368.38 |
| 分子式 | C21H20O6 |
| 可溶性/溶解性 | Soluble to 10 mM in DMSO and to 5 mM in ethanol |
| CAS号 | 458-37-7 |
| 参考文献 | Aggarwal and Sung (2009) Pharmacological basis for the role of curcumin in chronic diseases: an age-old spice with modern targets. TiPS 30 85. PMID: 19110321. Coleet al (2007) Neuroprotective effects of curcumin. Adv.Exp.Med.Biol. 595 197. PMID: 17569212. Kuttanet al (2007) Antitumour, anti-invasion, and antimetastatic effects of curcumin. Adv.Exp.Med.Biol. 595 173. PMID: 17569210. Lin (2007) Molecular targets of curcumin. Adv.Exp.Med.Biol. 595 227. PMID: 17569214. Miriyalaet al (2007) Cardioprotective effects of curcumin. Adv.Exp.Med.Biol. 595 359. PMID: 17569220. |