| 货号 | 0902/100 |
| 别名 | N-Cyano-N'-methyl-N''-[2-[(5-methyl-1H |
| 供应商 | Tocris |
| 生物活性 | Widely used H2 histamine antagonist which has more recently been described as an inverse agonist. Also a potent I1 imidazoline binding site ligand. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 252.34 |
| 分子式 | C10H16N6S |
| 可溶性/溶解性 | Soluble to 50 mM in water and to 100 mM in DMSO |
| CAS号 | 51481-61-9 |
| 参考文献 | Smitet al (1996) Inverse agonism of histamine H2 antagonists accounts for upregulation of spontaneously active receptors. Proc.Natl.Acad.Sci.U.S.A. 93 6802. PMID: 8692899. Tsoliet al (1995) The imidazoline I1 receptor agonist, moxonidine, inhibits insulin secretion from isolated rat islets of langerhans. Eur.J.Pharmacol. 284 199. PMID: 8549627. Ernsbergeret al (1992) A second generation of centrally acting antihypertensive agents act on putative I1-imidazoline receptors. J.Cardiovasc.Pharmacol. 20S1. Hill (1990) Distribution, properties and functional characteristics of three classes of histamine receptor. Pharmacol.Rev. 42 45. PMID: 2164693. |