| 货号 | 12990-25ug |
| 描述 | Prostaglandin D3(PGD3) is produced by the metabolism of EPA via the COX pathway.1 It is equipotent to PGD2 (Item No. 12010) in decreasing systemic blood pressure in rats and in decreasing intraocular pressure in rabbits.2,3,4 However, it is 3-5 times more potent than PGD2 in the inhibition of ADP-induced human platelet aggregation.2 |
| 别名 | PGD3; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Kulkarni, P.S.,Kaufman, P.L., and Srinivasan, B.D. Eicosapentaenoic acid metabolism in cynomolgus and rhesus conjunctiva and eyelid. Journal of Ocular Pharmacology 3, 349-356 (1987). 2.Bundy, G.L.,Morton, D.R.,Peterson, D.C., et al. Synthesis and platelet aggregation inhibiting activity of prostaglandin D analogues. Journal of Medicinal Chemistry 26, 790-799 (1983). 3.Goh, Y.,Nakajima, M.,Azuma, I., et al. Effects of prostaglandin D2 and its analogues on intraocular pressure in rabbits. Japanese Journal of Ophthamology 32, 471-480 (1988). 4.Kulkarni, P.S., and Srinivasan, B.D. Prostaglandins E3 and D3 lower intraocular pressure. Investigative Ophthalmology & Visual Science 26, 1178-1182 (1985). | |
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 350.5 |
| 分子式 | C20H30O5 |
| CAS号 | 71902-47-1 |
| 稳定性 | ≥ 1 year |
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