8-iso Prostaglandin A2
货号：
10235-500ug 基本售价：
924.0 元 规格：
500 ug
产品信息
概述| 货号 | 10235-500ug |
| 描述 | Isoprostanes are prostaglandin (PG)-like compounds produced in vivo by free radical-catalyzed peroxidation of arachidonoyl-containing lipids. 8-isoPGA2 is one of several isoprostanes produced from peroxidation of arachidonic acid esterified in phospholipids.18-isoPGA2 is the dehydration product of 8-isoPGE2, a potent renal vasoconstrictor.2 Evidence for the in vivo production of 8-isoPGA2 has been shown in rat liver under conditions of oxidative stress.3 There are no published studies of the pharmacological properties of 8-isoPGA2. |
| 别名 | 8-epiPGA2; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Morrow, J.D.,Minton, T.A.,Mukundan, C.R., et al. Free radical-induced generation of isoprostanes in vivo. Evidence for the formation of D-ring and E-ring isoprostanes. The Journal of Biological Chemisty 269, 4317-4326 (1994).
2.Longmire, A.W.,Roberts, L.J. and Morrow, J.D. Actions of the E2-isoprostane, 8-iso-PGE2, on the platelet thromboxane/endoperoxide receptor in humans and rats: Additional evidence for the existence of a unique isoprostane receptor. Prostaglandins 48, 247-256 (1994).
3.Chen, Y.,Zackert, W.E.,Robers, L.J., II, et al. Evidence for the formation of a novel cyclopentenone isoprostane, 15-A2t-isoprostane (8-iso-prostaglandin A2) in vivo. Biochemica et Biophysica Acta 1436, 550-556 (1999).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 334.5 |
| 分子式 | C20H30O4 |
| CAS号 | 474391-66-7 |
| 稳定性 | ≥ 1 year |
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