Furafylline
货号：
9000058-500ug 基本售价：
910.0 元 规格：
500 ug
产品信息
概述| 货号 | 9000058-500ug |
| 描述 | Furafylline is a selective inhibitor of human cytochrome P450 (CYP)1A2 (IC50 = 0.07 µM), demonstrating little effect on other CYP isoforms including 2D1, 2C, 3A, or 1A1.1 It was originally introduced as a bronchodilator with extended duration compared to theophylline, but then subsequently reported to inhibit the oxidation of caffeine (Item No. 14118), a reaction catalyzed by CYP1A2.1,2 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Sesardic, D.,Boobis, A.R.,Murray, B.P., et al. Furafylline is a potent and selective inhibitor of cytochrome P450IA2 in man. British Journal of Clinical Pharmacology 29(6), 651-663 (1990).
2.Tarrus, E.,Cami, J.,Roberts, D.J., et al. Accumulation of caffeine in healthy volunteers treated with furafylline. British Journal of Clinical Pharmacology 23(1), 9-18 (1987).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 260.3 |
| 分子式 | C12H12N4O3 |
| CAS号 | 80288-49-9 |
| 稳定性 | ≥ 2 years |
声明| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |
