Tyvelose
货号：
20910-1mg 基本售价：
910.0 元 规格：
1 mg
产品信息
概述| 货号 | 20910-1mg |
| 描述 | Tyvelose is an unusual 3,6-dideoxyhexose terminal sugar and the immunodominant component of glycoprotein antigens in the parasitic helminth T. spiralis, which is responsible for trichinosis in humans.1,2 It is produced in high amounts by the infective larva and is immunodominant during the muscle stage of infection. Mice immunized with tyvelose-BSA produce IgG1 antibodies to tyvelose but are not resistant to infection by T. spiralis.2 Tyvelose-specific antibodies (2.5 mg/20 g) administered to rat pups leads to expulsion of first stage larvae from the intestine within one hour.3 |
| 别名 | D-Tyvelose; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Wisnewski, N.,McNeil, M.,Grieve, R.B., et al. Characterization of novel fucosyl- and tyvelosyl-containing glycoconjugates from Trichinella spiralis muscle stage larvae. Mol. Biochem. Parasitol. 61(1), 25-35 (1993).
2.Goyal, P.K.,Wheatcroft, J. and Wakelin, D. Tyvelose and protective responses to the intestinal stages of Trichinella spiralis. Parasitol. Int. 51(1), 91-98 (2002).
3.Blum, L.K.,Mohanan, S.,Fabre, M.V., et al. Intestinal infection with Trichinella spiralis induces distinct, regional immune responses. Vet. Parasitol. 194(2-4), 101-105 (2013).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 148.2 |
| 分子式 | C6H12O4 |
| CAS号 | 1372925 |
| 稳定性 | ≥ 2 years |
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