ONO-RS-082
货号：
20243-20mg 基本售价：
910.0 元 规格：
20 mg
产品信息
概述| 货号 | 20243-20mg |
| 描述 | ONO-RS-082 is a reversible inhibitor of Ca2+-independent phospholipase A2.1 At 3.5 µM, it has been shown to inhibit epinephrine-stimulated thromboxane production in human platelets.1 ONO-RS-082 can also disrupt endosome tubule formation and maintenance of the Golgi complex.2,3 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Banga, H.S.,Simons, E.R.,Brass, L.F., et al. Activation of phospholipases A and C in human platelets exposed to epinephrine: Role of glycoproteins IIb/IIIa and dual role of epinephrine. Proc. Natl. Acad. Sci. USA 83(23), 9197-9201 (1986).
2.de Figueiredo, P.,Doody, A.,Polizotto, R.S., et al. Inhibition of transferrin recycling and endosome tubulation by phospholipase A2 antagonists. The Journal of Biological Chemisty 276(50), 47361-47370 (2001).
3.Bechler, M.E., and Brown, W.J. Gβ1γ2 activates phospholipase A2-dependent Golgi membrane tubule formation. Front. Cell. Dev. Biol. 2(4), (2014).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 371.9 |
| 分子式 | C21H22ClNO3 |
| CAS号 | 99754-06-0 |
| 稳定性 | ≥ 2 years |
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