Icosabutate
货号：
19386-500ug 基本售价：
910.0 元 规格：
500 ug
产品信息
概述| 货号 | 19386-500ug |
| 描述 | Icosabutate is a synthetic ω-3 polyunsaturated fatty acid derived from eicosapentaenoic alcohol and 2-bromo butyric acid. It was designed to resist β-oxidation and complex lipid incorporation and increase efficacy in fatty acid-responsive intracellular signaling systems.1,2 In a clinical trial, oral administration of icosabutate (600 mg) significantly reduced triglyceride, very low-density lipoprotein cholesterol, and Apo c-III levels in patients with very high triglyceride levels.1,2 |
| 别名 | PRB 01022;PRC 4016; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Bays, H.E.,Hallèn, J.,Vige, R., et al. Icosabutate for the treatment of very high triglycerides: A placebo-controlled, randomized, double-blind, 12-week clinical trial. J.Clin.Lipidol. 10(1), 181-191 (2016).
2.Kastelein, J.J.P.,Hallén, J.,Vige, R., et al. Icosabutate, a structurally engineered fatty acid, improves the cardiovascular risk profile in statin-treated patients with residual hypertriglyceridemia. Cardiology 135(1), 3-12 (2016).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 374.6 |
| 分子式 | C24H38O3 |
| CAS号 | 1253909-57-7 |
| 稳定性 | ≥ 1 year |
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