货号 | 11815-500mg |
描述 | Artemether is a natural product originally from plants of the genus Artemisia which effectively kills both malarial parasites P. falciparumandP. vivax(IC50 = 1.8 nM).1,2 It is usually used in combination with lumefantrine for the treatment of malaria.3 Arthemether also kills trematodes of the species Schistosoma, providing protection against schistosomiasis.4 Sesquiterpene lactones like artemether, artesunate, and artemisinin have potential applications in certain types of cancer and inflammatory conditions.5 |
别名 | Falcidol;Larither;Malartem;Paluther;SM-224; |
供应商 | Cayman |
应用文献 | |
1.Akoachere, M.,Buchholz, K.,Fischer, E., et al. In vitro assessment of methylene blue on chloroquine-sensitive and -resistant Plasmodium falciparum strains reveals synergistic action with artemisinins. Antimicrobial Agents and Chemotherapy 49(11), 4592-4597 (2005). 2.Pradines, B.,Ramiandrasoa, F.,Basco, L.K., et al. In vitro activities of novel catecholate siderophores against Plasmodium falciparum. Antimicrobial Agents and Chemotherapy 40(9), 2094-2098 (1996). 3.Mayxay, M.,Khanthavong, M.,Chanthongthip, O., et al. Efficacy of artemether-lumefantrine, the nationally-recommended artemisinin combination for the treatment of uncomplicated falciparum malaria, in southern Laos. Malar.J. 11(1), 1-17 (2012). 4.Liu, R.,Dong, H.F.,Guo, Y., et al. Efficacy of praziquantel and artemisinin derivatives for the treatment and prevention of human schistosomiasis: A systematic review and meta-analysis. Parasit.Vectors 4, 1-17 (2011). 5.Ghantous, A.,Gali-Muhtasib, H.,Saliba, N.A., et al. What made sesquiterpene lactones reach cancer clinical trials? Drug Discovery Today 15(15-16), 668-678 (2010). | |
运输条件 | Wet ice in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥98% |
计算分子量 | 298.4 |
分子式 | C16H26O5 |
CAS号 | 71963-77-4 |
稳定性 | ≥ 2 years |
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