| 货号 | 1312/10 |
| 别名 | [[4-Chloro-6-[(2,3-dimethylphenyl)a |
| 供应商 | Tocris |
| 生物活性 | Selective PPARα agonist (EC50 values are 0.63, 32 and > 100 μM at PPARα, PPARγ and PPARδ respectively). Negatively inhibits NF-κB transcriptional activity and decreases the inflammatory response in vitroandin vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >98 % |
| 计算分子量 | 323.8 |
| 分子式 | C14H14ClN3O2S |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| CAS号 | 50892-23-4 |
| 参考文献 | Bishop-Bailey (2000) Peroxisome proliferator-activated receptors in the cardiovascular system. Br.J.Pharmacol. 129 823. PMID: 10696077. Willsonet al (2000) The PPARs: from orphan receptors to drug discovery. J.Med.Chem. 43 527. PMID: 10691680. Formanet al (1997) Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors α and δ. Proc.Natl.Acad.Sci.U.S.A. 94 4312. PMID: 9113986. |