VU 0155041 (10 MG)
货号：
3248/10 基本售价：
882.3 元 规格：
10 mg
产品信息
概述| 货号 | 3248/10 |
| 别名 | cis-2-[[(3,5-Dichlorophenyl)amino]carbonyl]cyclohexanecarboxylic acid |
性能| 供应商 | Tocris |
| 生物活性 | Potent, positive allosteric modulator/allosteric agonist at mGlu4 receptors (EC50 = 798 and 693 nM at human and rat mGlu4 receptors respectively). Active in in vivo models of Parkinson's disease following i.c.v. administration. Also available as sodium salt (Cat. No. 3311). |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 316.18 |
| 分子式 | C14H15Cl2NO3 |
| 可溶性/溶解性 | Soluble to 100 mM in 1eq. NaOH and to 100 mM in DMSO |
| 参考文献 | Niswenderet al (2008) Discovery, characterization, and antiparkinsonian effect of novel positive allosteric modulators of metabotropic glutamate receptor 4. Mol.Pharmacol. 74 1345. PMID: 18664603. |
