| 货号 | 3850/50 |
| 别名 | Butanoic acid sodium salt |
| 供应商 | Tocris |
| 生物活性 | Histone deacetylase inhibitor. Restores contextual memory in a transgenic mouse model of Alzheimer's disease. Shown to induce pancreatic progenitor formation. Directs the differentiation of mouse embryonic stem cells into hepatocytes when used in combination with the cytokine Activin A. Also augments transcription factor stimulated iPSC generation. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 计算分子量 | 110.09 |
| 分子式 | C4H7NaO2 |
| 可溶性/溶解性 | Soluble to 100 mM in water |
| CAS号 | 156-54-7 |
| 参考文献 | Kilgoreet al (2010) Inhibitors of class 1 histone deacetylases reverse contextual deficits in a mouse model of Alzheimer's disease. Neuropsychopharmacology 35 870. PMID: 20010553. Lianget al (2010) Butyrate promotes induced pluripotent stem cell generation. J.Biol.Chem. 285 25516. PMID: 20554530. Renet al (2010) Effects of sodium butyrate on the differentiation of pancreatic and hepatic progenitor cells from mouse embryonic stem cells. J.Cell Biochem. 109 236. PMID: 19911386. Zhouet al (2010) Differentiation of mouse embryonic stem cells into hepatocytes induced by a combination of cytokines and sodium butyrate. J.Cell Biochem. 109 606. PMID: 20039312. Boffaet al (1978) Suppression of histone deacetylation in vivo and in vitro by sodium butyrate. J.Biol.Chem. 253 3364. PMID: 649576. |