| 货号 | 4308/50 |
| 别名 | (1R)-2,3-Dihydro-N-2-propynyl-1H-in |
| 供应商 | Tocris |
| 生物活性 | Selective irreversible MAO-B inhibitor. Displays antiParkinsonian activity; exhibits neuroprotective and antiapoptotic activity against several neurotoxins in cell culture. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 267.34 |
| 分子式 | C12H13N.CH3SO |
| 可溶性/溶解性 | Soluble to 100 mM in water and to 100 mM in DMSO |
| 参考文献 | Finberg and Youdim (2002) Pharmacological properties of the anti-Parkinson drug rasagiline; modification of endogenous brain amines, reserpine reversal, serotonergic and dopaminergic behaviours. Neuropharmacology 43 1110. PMID: 12504917. Maruyamaet al (2002) The anti-parkinson drug, rasagiline, prevents apoptotic DNA damage induced by peroxynitrite in human dopaminergic neuroblastoma SH-SY5Y cells. J.Neural Transm. 109 467. PMID: 11956966. Youdim and Weinstock (2002) Molecular basis of neuroprotective activities of rasagiline and the anti-Alzheimer drug TV3326 [(N-propargyl-(3R)aminoindan-5-YL)-ethyl methyl carbamate]. Cell.Mol.Neurobiol. 21555. |