货号 | 1967/50 |
别名 | N-[2-[[[5-[(Dimethylamino)methyl]-2 |
供应商 | Tocris |
生物活性 | Potent, selective and competitive histamine H2 receptor antagonist (pA2 = 6.95 - 7.2). Inhibits gastric acid secretion induced by histamine, pentagastrin, bethanecol and food in vivo. Also inhibits aspirin-induced gastric lesions. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
纯度 | >99 % |
计算分子量 | 350.86 |
分子式 | C13H22N4O3S.HCl |
可溶性/溶解性 | Soluble to 50 mM in water |
CAS号 | 66357-35-5 |
参考文献 | Brittain and Daly (1981) A review of the animal pharmacology of ranitidine - a new, selective histamine H2-antagonist. Scand.J.Gastroenterol.Suppl. 691. Dalyet al (1981) Some in vitroandin vivo actions of the new histamine H2-receptor antagonist, ranitidine. Br.J.Pharmacol. 72 49. PMID: 6112034. Dalyet al (1981) Antagonism of vasodepressor and gastric secretory responses to histamine by the H2-receptor antagonists, ranitidine and cimetidine, in the anaesthetized dog. Br.J.Pharmacol. 72 55. PMID: 6112035. |