| 货号 | 4241/10 |
| 别名 | (Z)-11-[3-(Dimethylamino)propyliden |
| 供应商 | Tocris |
| 生物活性 | Histamine H1 receptor antagonist (Ki = 31.6 nM). Inhibits the release of histamine, prostaglandin D2 and tryptase in a concentration-dependent manner. Mast cell stabilizer; inhibits mast cell mediator release. Also suppresses inflammation by inhibition of cytokine production. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 373.87 |
| 分子式 | C21H23NO3.HCl |
| 可溶性/溶解性 | Soluble to 75 mM in water and to 100 mM in DMSO |
| 参考文献 | Tamuraet al (2007) Olopatidine ameliorates rat experimental cutaneous inflammation by improving skin barrier function. Pharmacology 81 118. PMID: 17962722. Sharifet al (1996) Characterization of the ocular antiallergic and antihistaminic effects of olopatidine (AL-4943A), a novel drug for treating ocular allergic diseases. J.Pharm.Exp.Ther. 2781252. |