| 货号 | 4225/10 |
| 别名 | Octadecyltrimethylammonium bromide |
| 供应商 | Tocris |
| 生物活性 | Dynamin inhibitor (IC50 = 1.9 μM for dynamin I). Inhibits receptor-mediated endocytosis (IC50 = 16 μM). Displays similar activity to MitMAB (Cat. No. 4224). |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 计算分子量 | 392.5 |
| 分子式 | C21H46BrN |
| 可溶性/溶解性 | Soluble to 10 mM in DMSO and to 100 mM in ethanol |
| 参考文献 | Joshiet al (2010) The dynamin inhibitors MitMAB and OctMAB induce cytokinesis failure and inhibit cell proliferation in human cancer cells. Mol.Cancer Ther. 9 1995. PMID: 20571068. Quanet al (2007) Myristyl trimethyl ammonium bromide and octadecyl trimethyl ammonium bromide are surface-active small molecule dynamin inhibitors that block endocytosis mediated by dynamin I or dynamin II. Mol.Pharmacol. 72 1425. PMID: 17702890. |