货号 | 1384/10 |
别名 | 4-[[[(3-Chlorophenyl)amino]carbonyl |
供应商 | Tocris |
生物活性 | Selective muscarinic M1 receptor agonist. Selectivity for M1 over other muscarinic receptor types appears to arise from a high efficacy at M1receptors. |
运输条件 | Blue Ice |
存放说明 | Ambient |
纯度 | >99 % |
计算分子量 | 317.21 |
分子式 | C14H18Cl2N2O2 |
可溶性/溶解性 | Soluble to 100 mM in water |
CAS号 | 55-45-8 |
参考文献 | Davieset al (2001) Inhibition of field stimulation-induced contractions of rabbit vas deferens by muscarinic receptor agonists: selectivity of McN-A-343 for M1 receptors. J.Pharm.Pharmacol. 53 487. PMID: 11341365. Eglenet al (1996) Muscarinic receptor subtypes and smooth muscle function. Pharmacol.Rev. 48 531. PMID: 8981565. Micheletti and Schiavone (1990) Functional determination of McN-A-343 affinity for M1 muscarinic receptors. J.Pharmacol.Exp.Ther. 253 310. PMID: 1691785. |