货号 | 0219/1G |
别名 | Aminoethanoic acid |
供应商 | Tocris |
生物活性 | One of the major inhibitory neurotransmitters in the mammalian CNS, predominantly active in the spinal cord and brain stem. Also acts as a modulator of excitatory amino acid transmission mediated by NMDA receptors. Also available as part of the NMDA Receptor - Glycine Site Tocriset™. |
运输条件 | Blue Ice |
存放说明 | Ambient |
计算分子量 | 75.07 |
分子式 | C2H5NO2 |
可溶性/溶解性 | Soluble to 100 mM in water |
参考文献 | Kuhseet al (1995) The inhibitory glycine receptor: architecture, synaptic localization and molecular pathology of a postsynaptic ion-channel complex. Curr.Opin.Neurobiol. 5 318. PMID: 7850154. Betz (1991) Glycine receptors: heterogeneous and widespread in the mammalian brain. Trends Neurosci. 14 458. PMID: 1722365. Ascher and Johnson (1989) The NMDA receptor, its channel and its modulation by glycine. The NMDA Receptor (2nd edition). Eds. G.L.Collingr 109. Johnson and Ascher (1987) Glycine potentiates the NMDA response in cultured mouse brain neurons. Nature 325529. |