| 货号 | 1110/10 |
| 别名 | 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4 |
| 供应商 | Tocris |
| 生物活性 | Phytoestrogen with a wide range of biological actions. Inhibits protein tyrosine kinases including epidermal growth factor receptor kinase. Also binds to PPARγ and estrogen receptors and acts as an agonist at GPER. Also available as part of the MAPK Cascade Inhibitor Tocriset™. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 270.24 |
| 分子式 | C15H10O5 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| CAS号 | 446-72-0 |
| 参考文献 | Danget al (2003) Peroxisome proliferator-activated receptor γ (PPARγ) as a molecular target for the soy phytoestrogen genistein. J.Biol.Chem. 278 962. PMID: 12421816. Migitaet al (1994) Prevention of anti-CD3 monoclonal antibody-induced thymic apoptosis by protein tyrosine kinase inhibitors. J.Immunol. 153 3457. PMID: 7523495. Linassieret al (1990) Mechanisms of action in NIH-3T3 cells of genistein, an inhibitor of EGF receptor tyrosine kinase activity. Biochem.Pharmacol. 39 187. PMID: 2153378. Akiyamaet al (1987) Genistein, a specific inhibitor of tyrosine-specific protein kinases. J.Biol.Chem. 262 5592. PMID: 3106339. Merck Index 124395. |