DMNB (10 MG)
货号：
2088/10 基本售价：
882.3 元 规格：
10 mg
产品信息
概述| 货号 | 2088/10 |
| 别名 | 4,5-Dimethoxy-2-nitrobenzaldehyde |
性能| 供应商 | Tocris |
| 生物活性 | Inhibitor of DNA-dependent protein kinase (DNA-PK) (IC50 = 15 μM), an enzyme involved in the non-homologous end-joining (NHEJ) pathway of double-stranded DNA break (DSB) repair in human cells. Displays 100-fold higher potency than its analog vanillin and does not affect PKC activity. Produces lethal effects on cisplatin-treated D5037 cells upon continuous exposure. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 211.15 |
| 分子式 | C9H9NO5 |
| 可溶性/溶解性 | Soluble to 25 mM in ethanol with gentle warming and to 100 mM in DMSO |
| CAS号 | 20357-25-9 |
| 参考文献 | Durant and Karran (2003) Vanillins - a novel family of DNA-PK inhibitors. Nucleic Acids Res. 31 5501. PMID: 14500812. |
