Daminozide (50 MG)
货号：
4684/50 基本售价：
882.3 元 规格：
50 mg
产品信息
概述| 货号 | 4684/50 |
| 别名 | 1-(2,2-Dimethylhydrazide)butanedioic acid |
性能| 供应商 | Tocris |
| 生物活性 | Histone demethylase KDM2/7 subfamily inhibitor (IC50 values are 0.55, 1.5 and 2.1 μM for PHF8, KDM2A and KDM7A respectively). Exhibits ≥ 60-fold selectivity for KDM2/7 demethylases over other histone demethylases and 2-oxoglurate oxygenases (IC50 > 100 μM). |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 计算分子量 | 160.17 |
| 分子式 | C6H12N2O3 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 100 mM in water |
| 参考文献 | Roseet al (2012) Plant growth regulator daminozide is a selective inhibitor of human KDM2/7 histone demethylases. J.Med.Chem. 55 6639. PMID: 22724510. |
