| 货号 | 2577/50 |
| 别名 | [2-[4-[(4-Chlorophenyl)phenylmethyl |
| 供应商 | Tocris |
| 生物活性 | Histamine H1 receptor antagonist that displays selectivity over other receptors at concentrations up to 10 μM. A non-sedating antihistamine that inhibits histamine release and eosinophil chemotaxis during secondary phase allergic response. Inhibits activation of eosinophils, neutrophils and monocytes in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 461.81 |
| 分子式 | C21H25ClN2O3.2HCl |
| 可溶性/溶解性 | Soluble to 100 mM in water and to 100 mM in DMSO |
| CAS号 | 83881-52-1 |
| 参考文献 | Walshet al (1991) Effects of cetirizine on human eosinophil and neutrophil activation in vitro. Int.Arch.Allergy Appl.Immunol. 95 158. PMID: 1682275. Campoli-Richardset al (1990) Cetirizine. A review of its pharmacological properties and clinical potential in allergic rhinitis, pollen-induced asthma, and chronic urticaria. Drugs 40 762. PMID: 1981354. Snowman and Snyder (1990) Cetirizine: actions on neurotransmitter receptors. J.Allergy.Clin.Immunol. 86 1025. PMID: 1979798. |